Bioactive Small Molecules
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Filtered Search Results
STEMCELL Technologies LDN193189 (Dihydrochloride), Size: 10 mg
Inhibit ALK1, ALK2, ALK3, and ALK6 with LDN193189 (Sanvitale et al. PLoS One, 2013). This bone morphogenetic (BMP) pathway inhibitor promotes the differentiation of human pluripotent stem cells to neural progenitor cells (Chambers et al. Nat Biotechnol, 2012; Kriks et al. Nature, 2011) and neural crest cells (Kreitzer et al. Am J Stem Cells, 2013). LDN193189 is used in cancer research to prevent ovarian cancer cell proliferation (Tsai et al. Cell Rep, 2012) and inhibit prostate and breast cancer tumor growth (Balboni et al. Cancer Res, 2013; Lee et al. Neuropsychopharmacology, 2016). It also promotes the differentiation of sensory epithelial cells of the inner ear from mouse embryonic stem cells (Koehler et al. Nature, 2013). LDN193189 is supplied as the dihydrochloride hydrate form of the molecule with > 98% purity; Molecular weight 479.4 g/mol; CAS Number 1435934-00-1. Visit STEMCELL.com for more information and related products.
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STEMCELL Technologies Y-27632 (Dihydrochloride), Size: 1 mg
Inhibit Rho-associated, coiled-coil containing protein kinase (ROCK), including both ROCK1 and ROCK2 (Davies et al. Biochem J, 2000; Ishizaki et al. Mol Pharmacol, 2000), with Y-27632. Y-27632 enhances the survival and increases the cloning efficiency of human embryonic stem (ES) cells (Watanabe et al. Nat Biotechnol, 2007), improves embryoid body formation using forced-aggregation protocols (Ungrin et al. PLoS One, 2008), and increases the survival of cryopreserved single human ES cells after thawing (Li et al. Hum Reprod, 2009). In combination with other factors, it allows for the direct lineage reprogramming of fibroblasts to mature neurons (Hu et al. Cell Stem Cell, 2015). Y-27632 also improves survival of human ES cell monolayers at the initiation of differentiation protocols (Rezania et al. Nat Biotechnol, 2014). Y-27632 is supplied as a crystalline solid with ≥ 98% purity; Molecular weight 320.3 g/mol; CAS number 129830-38-2. Visit STEMCELL.com for more information.
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Medchemexpress LLC Forskolin 10 Mm 1 Ml In Dmso | HY-15371-10MM 1ML/DMSO
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Forskolin 10 Mm 1 Ml In Dmso
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STEMCELL Technologies DAPT, Size: 5 mg
Inhibit the γ-secretase complex, indirectly inhibiting the Notch pathway with DAPT. This notch pathway inhibitor promotes the differentiation of human pluripotent stem cells into nociceptors (Chambers et al. Nature Biotechnol, 2012) and pancreatic cells (D'Amour et al. Nature Biotechnol, 2006). It is also used to promote the differentiation of mouse embryonic stem cells to neurons (Crawford and Roelink. Dev Dyn, 2007) and retinal pigment epithelium (Osakada et al. Nat Protoc, 2009). DAPT also reduces colony-forming efficiency of mouse neural stem cells (Androutsellis-Theotokis et al. Nature, 2006) and reduces mammosphere-forming efficiency of breast cancer cell lines and ductal carcinoma in situ cells (Farnie et al. J Natl Cancer, 2007; Harrison et al. Cancer Res, 2010). DAPT is supplied as a crystalline solid with ≥95% purity; Molecular weight 432.5 g/mol; CAS Number 208255-80-5. Visit STEMCELL.com for more information and related products.
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ANALYTICHEM CANADA INC CB3-001-151
NC3740711 CB3-001-151
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Medchemexpress LLC Exatecan (Synonyms: DX-8951) 5mg, Solid, | CAS No. : 171335-80-1
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Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.
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Sigma Aldrich Fine Chemicals Biosciences Stainless steel 304 syringe needle gauge 18, L 12 in. | 1EA
Stainless steel 304 syringe needle gauge 18, L 12 in. | 1EA
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Medchemexpress LLC Exatecan-D5 Mesylate 5Mg | HY-13631AS-5MG
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Exatecan-D5 Mesylate 5Mg
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KEY SCIENTIFIC PRODUCTS XYLOSE FERMENT TABLETS 50BT
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NC2245683 XYLOSE FERMENT TABLETS 50BT
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Medchemexpress LLC Sorafenib 10Mm/1Ml In Dmso | HY-10201-1ML
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Sorafenib 10Mm/1Ml In Dmso
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Medchemexpress LLC Gsk2606414 10Mm 1Ml Dmso Recon | HY-18072-10MM1MLDMSO
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Gsk2606414 10Mm 1Ml Dmso Recon
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Medchemexpress LLC GCN2iB | 2183470-12-2 | MFCD31692416 | 10 mM * 1 mL in DMSO
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GCN2iB | Putity: 99.81% | MW: 451.83 | 2183470-12-2 | MFCD31692416 | 10 mM * 1 mL in DMSO
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Selleck Chemical LLC Tirzepatide, 5 mg, synthetic dual agonist for GIP and GLP-1 receptors, powder
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Tirzepatide (LY3298176) sodium is a high-purity, synthetic dual agonist for GIP and GLP-1 receptors, recognized for its effectiveness in promoting glucose-dependent insulin secretion and enhancing glucose tolerance. This compound is noted for its potential to aid in weight reduction and improving metabolic parameters.
- High purity: 99.96%
- 99% plasma protein binding to albumin
- Molecular weight: 4813 g/mol
- CAS number: 2023788-19-2
- Storage stability: 3 years at -20°C (powder), 1 year at -80°C (aliquoted stock solutions)
- Solubility in DMSO: 100 mg/mL (20.77 mM)
- Peptide length: 39 amino acids
- Chemical modification for improved stability and uptake
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BIORBYT LLC
NC4044611 PHOSPHO-GCN2 THR899 RAB 200UL
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KOOLANCE INC Koolance 702 Liquid Coolant, High-Performance, UV Blue, 5000ml (169 fl oz)
Koolance 702 series coolant is used by many industries requiring a high performance, low-toxicity, reliable coolant with corrosion and biological inhibitors. A high quality coolant is extremely important for addressing dissimilar metals and biologic growth (bacterial and algae) long-term. Koolance liquids will not clog components and can typically be used for 2-3 years before replacement is recommended. (Coolant shelf life is 3 years.)This container includes 5 liters (169 fl oz) of prediluted coolant. It's recommended to replace the coolant at least every 2-3 years, or immediately if there is any change in color or clarity.The freezing point is -15°C (5°F). This coolant has been tested with the following materials:Metals: copper, brass, aluminum, stainless steel, nickel, steel, gold, leadPlastics: ABS, PA66, PBT, PE, PEI, PES, PETG, PMMA, POM, PP, PPE, PPO, PPS, PTFE, PU, PVCRubber: EPDMNOTE: Not recommended for polycarbonate
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